Flea & Tick Dog Products Comparison
PetSmart PetSmart
Even very clean, pampered dogs can get fleas and ticks if pet parents don't stay on top of certain preventative steps. These preventative steps seek to minimize or eliminate a dog's chance of being a feeding ground for pesky fleas and ticks and include:
Even very clean, pampered dogs can get fleas and ticks if pet parents don't stay on top of certain preventative steps. These preventative steps seek to minimize or eliminate a dog's chance of being a feeding ground for pesky fleas and ticks and include:
- Vacuuming your home often.
- Washing the areas outside of your home often--fleas and ticks don't like water.
- Grooming your dog frequently to check for fleas and ticks.
- Using topical adulticide and insect growth regulators (IGRs) products. Adulticides are compounds that kill and repel adult fleas, ticks, and other insects. IGRs, mimic a naturally occurring insect hormone that interferes with normal flea development, preventing immature pests from becoming adults that reproduce and continue the lifecycle.
The last step is the most effective in ongoing protection against fleas and ticks. Yet for years, the only way pet parents could obtain topical, ongoing flea and tick control products for their dogs, was via a prescription through their veterinarian. However, non-prescription flea and tick products have come a long way since then and rival many of their prescription counterparts in safety and effectiveness, while being less expensive.
PetSmart offers several safe and effective flea and tick solutions comparable to the leading prescription brands. View the following flea and tick product comparison chart to see how our products compare to the leading prescription brands.
| Product | HARTZ® Advanced Care 4-in-1 Flea & Tick Drops Plus | Zodiac® Spot On | Bio Spot® | Sentry Pro | K9 Advantix | Frontline® Plus |
| Availability | Over the counter | Over the counter | Over the counter | Over the counter | Vet only | Vet only |
| Application | Topical Spot-on |
Topical Spot-on |
Topical Spot-on |
Topical Spot-on |
Topical Spot-on |
Topical Spot-on |
| Insect growth regulator | Yes | No | Yes | Yes | No | Yes |
| Repels/kills adult fleas | Yes | Yes | Yes | Yes | Yes | Yes |
| Kills flea eggs | Yes | Yes | 4 months | 4 months | Yes | Yes |
| Kills flea larva | Yes | Yes | 4 months | 4 months | Yes | Yes |
| Kills dog ticks | Yes | Yes | Yes | Yes | Yes | Yes |
| Kills deer ticks | Yes | Yes | Yes | Yes | Yes | No |
| Repels ticks | Yes | Yes | Yes | Yes | Yes | No |
| Repels/kills mosquitoes | Yes | Yes | Yes | Yes | Yes | No |
| Age restriction | 12 weeks & older | 24 weeks & older | 12 weeks & older | 12 weeks & older | 7 weeks & older | 8 weeks & older |
For best results, read the product label and follow the directions of all health products.
CAUTION: Never use a flea and tick product intended for dogs on cats, as it could fatally affect the cat.

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